Alvaro Arbeloa will partner Jamie Carragher at the heart of Liverpool's defence at City in the absence of the injured Sami Hyypia.
The match kicks off at 4pm GMT – and you can listen live online.
The Reds XI in full is: Reina, Aurelio, Finnan, Carragher, Arbeloa, Benayoun, Kewell, Mascherano, Gerrard, Kuyt, Torres. Subs: Itandje, Riise, Alonso, Voronin, Babel.